A recent report by the Inter-governmental Panel on Climate Change suggests that extreme weather and climate conditions in the future are very likely, which will lead to increase in the rate of sea level rise, heavy precipitation, and stronger hurricanes. These climate-related coastal hazards, when compounded with the natural and social environments, could lead to very devastating effects. It is widely known that even to the same type of hazard, the vulnerability and resilience of different regions could be very different. Hence, identifying the factors that make a place more resilient to hazards is critical to its long-term sustainability and is central to climate change research and planning. This seminar will first outline the issues related to resilience assessment and introduce their resilience research practiced in different hazard types and regions. Then, it will extend the static assessment to dynamic system modeling and discuss the issues involved in coupled natural-human dynamics modeling, using the examples from our study of the Mississippi River Delta region in Louisiana. We will conclude with some perspectives on the methods, approaches, and implications for research in human dynamics and climate change.